Outlook
In short: Outlook is Microsoft’s e-mail and calendar program as well as the associated web service outlook.com.
In more detail: The desktop program belongs to Microsoft 365. It manages mails, appointments, contacts and tasks and can integrate several accounts (Exchange, IMAP).
In Depth
Protocols
IMAP and SMTP for any provider, Exchange/Microsoft Graph in companies.
Security
Outlook is a frequent target for phishing. Never open macros and attachments from unknown senders. See Gmail, Microsoft.