Downloader Trojan
In short: A downloader trojan loads further malware after infection.
In more detail: It is small and inconspicuous so that it evades virus scanners more easily. Its only job: contact a server, download the actual payload (ransomware, infostealer, bot) and start it.
In Depth
Business model
The infection is resold as a service (“loader”). Emotet and Smoke Loader worked this way.
Protection
Block macros, allow scripts only if signed, monitor outgoing traffic, anti-malware with behaviour detection.
See also: Trojans, E-mail Attachments, Botnets